2-Amino-5-bromobenzenesulfonamide → HCID 57750934, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[S:9]([NH2:12])(=[O:11])=[O:10].[Cl:13][C:14]1[CH:15]=[C:16]([C:21]2[CH:22]=[C:23]([S:27](Cl)(=[O:29])=[O:28])[CH:24]=[CH:25][CH:26]=2)[CH:17]=[CH:18][C:19]=1[Cl:20]>N1C=CC=CC=1>[Br:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][S:27]([C:23]2[CH:24]=[CH:25][CH:26]=[C:21]([C:16]3[CH:17]=[CH:18][C:19]([Cl:20])=[C:14]([Cl:13])[CH:15]=3)[CH:22]=2)(=[O:29])=[O:28])=[C:3]([S:9]([NH2:12])(=[O:11])=[O:10])[CH:4]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
2-Amino-5-bromobenzenesulfonamide (0.60 g, 2.39 mmol) was dissolved in pyridine (6 ml) and 3-(3,4-dichlorophenyl)-phenylsulfonyl chloride (0.82 g, 2.51 mmol) was added and the reaction stirred overnight. The solvent was removed in vacuo and the residue was purified by preparative HPLC (XTerra MS C8 column, acetonitrile/ammonium acetate buffer) to give the title compound (0.70 g, 55% yield).