2-Amino-5-cyanobenzene-1-sulfonamide → (E)-2-(2-(4-Chloro-2-methoxyphenyl)vinylsulfonamido)-5-cyanobenzenesulfonamide
Reaktionsgleichung
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]#[N:9])=[CH:4][C:3]=1[S:10]([NH2:13])(=[O:12])=[O:11].[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([CH:21]=[CH:22][S:23](Cl)(=[O:25])=[O:24])=[C:17]([O:27][CH3:28])[CH:16]=1>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18](/[CH:21]=[CH:22]/[S:23]([NH:1][C:2]2[CH:7]=[CH:6][C:5]([C:8]#[N:9])=[CH:4][C:3]=2[S:10]([NH2:13])(=[O:11])=[O:12])(=[O:24])=[O:25])=[C:17]([O:27][CH3:28])[CH:16]=1Komponenten
3
Versuchsvorschrift
The title compound was synthesized as described for Example 178 in 27% yield, starting from 2-amino-5-cyanobenzenesulfonamide and 2-(4-chloro-2-methoxy-phenyl)-ethenesulfonyl chloride.
Quellen und Nachweise
- ORD-Eintrag
- ord-1d4cb220e6534dcd81749710e6e1676d
- Quelldatensatz
- uspto-grants-2015_09