Methanol → HCID 57750991, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][S:10]([NH:13][C:14]2[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][C:15]=2[S:23](=[O:26])(=[O:25])[NH2:24])(=[O:12])=[O:11])=[C:4]([O:27][CH3:28])[CH:3]=1.[CH3:29]O>S(Cl)(Cl)=O>[CH3:29][O:19][C:18](=[O:20])[C:17]1[CH:21]=[CH:22][C:14]([NH:13][S:10]([CH2:9][CH2:8][C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][C:4]=2[O:27][CH3:28])(=[O:12])=[O:11])=[C:15]([S:23](=[O:25])(=[O:26])[NH2:24])[CH:16]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of 4-[2-(4-chloro-2-methoxy-phenyl)-ethanesulfonylamino]-3-sulfamoyl-benzoic acid (0.18 g, 0.40 mmol) in anhydrous methanol (15 mL), thionyl chloride (1 mL) was added and the mixture was heated at reflux for 18 hours. The volatiles were removed under reduced pressure to give 0.18 g (97% yield) of the title compound.