N-cyclopropyl-4-formylbenzamide → N-cyclopropyl-4-(5-(4-(2-hydroxyethoxy)benzamido)-1H-benzo[d]imidazol-2-yl)benzamide
Reaktionsgleichung
[N+:1]([C:4]1[CH:5]=[C:6]([NH:13][C:14](=[O:25])[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH2:22][CH2:23][OH:24])=[CH:17][CH:16]=2)[CH:7]=[CH:8][C:9]=1[N+:10]([O-])=O)([O-])=O.[CH:26]1([NH:29][C:30]([C:32]2[CH:39]=[CH:38][C:35]([CH:36]=O)=[CH:34][CH:33]=2)=[O:31])[CH2:28][CH2:27]1>>[CH:26]1([NH:29][C:30](=[O:31])[C:32]2[CH:39]=[CH:38][C:35]([C:36]3[NH:10][C:9]4[CH:8]=[CH:7][C:6]([NH:13][C:14](=[O:25])[C:15]5[CH:20]=[CH:19][C:18]([O:21][CH2:22][CH2:23][OH:24])=[CH:17][CH:16]=5)=[CH:5][C:4]=4[N:1]=3)=[CH:34][CH:33]=2)[CH2:27][CH2:28]1Komponenten
3
Versuchsvorschrift
Compound 237 was prepared according to the procedure similar to that described in Scheme III from N-(3,4-dinitrophenyl)-4-(2-hydroxyethoxy)benzamide and 4-cyclopropylaminocarbonylbenzaldehyde. [M+H]+ calcd for C26H24N4O4: 457.19; found: 457.51.
Quellen und Nachweise
- ORD-Eintrag
- ord-ae85fa376c63455ba7902cc71726de6f
- Quelldatensatz
- uspto-grants-2015_09