Reaktionsgleichung
CO[C:3]([C:5]1[CH:14]=[CH:13][C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:15]([OH:17])=[O:16])[CH:11]=2)[CH:6]=1)=[O:4].[CH2:18]([CH2:20][NH2:21])[OH:19]>>[OH:19][CH2:18][CH2:20][NH:21][C:3]([C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[CH:11]=[C:10]([C:15]([OH:17])=[O:16])[CH:9]=[CH:8]2)=[O:4]Komponenten
3
Versuchsvorschrift
2.1 g of naphthalene-2,6-dicarboxylic acid monomethyl ester and 25 ml of ethanolamine are heated at 150° C. for 3 h. The excess ethanolamine is distilled off in vacuo, and the residue is dissolved in water and the mixture is extracted with ethyl acetate. After acidifying the aqueous phase, the product which is deposited is filtered off with suction and recrystallized from ethanol. 1.2 g of 6-(2-hydroxyethyl-aminocarbonyl)-2-naphthoic acid are obtained.
Aufarbeitung
- distillationThe excess ethanolamine is distilled off in vacuo
- dissolutionthe residue is dissolved in water
- extractionthe mixture is extracted with ethyl acetate
- filtrationthe product which is deposited is filtered off with suction
- customrecrystallized from ethanol
Quellen und Nachweise
- ORD-Eintrag
- ord-7f7238c97ffa4653a3967569cb05ce1a
- Quelldatensatz
- uspto-grants-2000_07
- Patentnummer
- US06087304
Verknüpfte Notizen
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