Trifluoroacetic acid → HCID 178462042, Verbindung

HRID 2289067Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2289067
[N+:1]([C:4]1[CH:47]=[CH:46][C:7]([CH2:8][O:9][C:10]([N:12]=[C:13]([NH:32][C:33]([O:35][CH2:36][C:37]2[CH:42]=[CH:41][C:40]([N+:43]([O-:45])=[O:44])=[CH:39][CH:38]=2)=[O:34])[NH:14][C@H:15]([CH3:31])[C:16]([NH:18][C@H:19]2[CH2:23][CH2:22][N:21](C(OC(C)(C)C)=O)[CH2:20]2)=[O:17])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[F:48][C:49]([F:54])([F:53])[C:50]([OH:52])=[O:51]>ClCCl>[F:48][C:49]([F:54])([F:53])[C:50]([OH:52])=[O:51].[N+:1]([C:4]1[CH:47]=[CH:46][C:7]([CH2:8][O:9][C:10]([N:12]=[C:13]([NH:32][C:33]([O:35][CH2:36][C:37]2[CH:38]=[CH:39][C:40]([N+:43]([O-:45])=[O:44])=[CH:41][CH:42]=2)=[O:34])[NH:14][C@H:15]([CH3:31])[C:16]([NH:18][C@H:19]2[CH2:23][CH2:22][NH:21][CH2:20]2)=[O:17])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

4

Edukt 2

HCID 6422Trifluoroacetic acidHCID 178462047HCID 178462047, Verbindung

Produkt 1

HCID 178462042HCID 178462042, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a solution of the compound (1.087 g), which had been obtained in (1), in anhydrous dichloromethane (5 ml), trifluoroacetic acid (2 ml) was added dropwise under ice cooling. The resulting mixture was treated in a similar manner to that described in Referential Example 16-(2), whereby the title compound was obtained. The product was provided for use in the subsequent reaction without isolation, Infrared absorption spectrum (KBr) νmax cm-1 : 3290, 1739, 1674, 1645, 1625, 1555, 1524.

Aufarbeitung

  1. additionThe resulting mixture was treated in a similar manner to that

Quellen und Nachweise

ORD-Eintrag
ord-a08044e24a77477fa7c7d41b04679be0
Quelldatensatz
uspto-grants-2000_07
Patentnummer
US06090802

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