7-(Acetylamino)-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamide → 6-(Acetylamino)-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamide

HRID 2289918Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2289918
[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][C:6]([C:12]([NH:14][CH2:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=1)=[O:13])=[C:5]2[OH:23].[C:24](NC1C=C2C(C(O)=C(C(NCC3C=CC(Cl)=CC=3)=O)C=N2)=CC=1)(=[O:26])[CH3:25].NC1C=C2C(C(O)=C(C(NCC3C=CC(Cl)=CC=3)=O)C=N2)=CC=1>>[C:24]([NH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][C:6]([C:12]([NH:14][CH2:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=1)=[O:13])=[C:5]2[OH:23])(=[O:26])[CH3:25]

Komponenten

4

Edukt 3

HCID 1784740467-(Acetylamino)-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamideHCID 178507324HCID 178507324, VerbindungHCID 1785073346-amino-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamide

Produkt 1

HCID 1784740596-(Acetylamino)-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamide

Versuchsvorschrift

This compound is prepared from 6-amino-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamide using a procedure similar to that used to prepare 7-(acetylamino)-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamide from 7-amino-N-[(4-chlorophenyl)methyl]-4-hydroxy-3-quinolinecarboxamide. The product is obtained as a tan powder.

Aufarbeitung

  1. customThe product is obtained as a tan powder

Quellen und Nachweise

ORD-Eintrag
ord-8b44cd2f81d54045871ef3802742a76f
Quelldatensatz
uspto-grants-2000_07
Patentnummer
US06093732

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