(2-Thienylmethyl)amine → 3-(3,5-Dichloro-2-hydroxyphenyl)-3-{(5-oxo-1-(3-{((2-thienylmethyl)amino)carbonylamino}phenyl)pyrrolidin-3-yl)carbonylamino}propanoic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	(2-Thienylmethyl)amine	HCID 34005	—
Edukt	3-(3-Fluorophenyl)-3-{(5-oxo-1-(3-{(benzylamino)carbonylamino}phenyl)pyrrolidin-3-yl)carbonylamino}propanoic acid	HCID 22591754	—
Edukt	Ethyl 3-amino-3-(3,5-dichloro-2-hydroxyphenyl)propanoate	HCID 22591801	—
Produkt	3-(3,5-Dichloro-2-hydroxyphenyl)-3-{(5-oxo-1-(3-{((2-thienylmethyl)amino)carbonylamino}phenyl)pyrrolidin-3-yl)carbonylamino}propanoic acid	HCID 10167402	—

Reaktionsschritte

The title compound was analogously synthesized to the preparation of 3-(3-fluorophenyl)-3-{(5-oxo-1-(3-{(benzylamino)carbonylamino}phenyl)pyrrolidin-3-yl)carbonylamino}propanoic acid from ethyl 3-amino-3-(3,5-dichloro-2-hydroxyphenyl)propanoate and 2-thienylmethyl amine. MS (ES+): 591 (M+H)+; (ES−): 589 (M−H)−.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06849639B2
Quelldatensatz	uspto-grants-2005_02
ORD ID	ord-2dcac970ba41443aa25c723595a5a9dc
Quellennotiz	uspto-grants-2005_02