L-Alanine → (S)-2-(phenylsulfonamido)propanoic acid

HRID 2290957Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2290957
[NH2:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3].[C:7]1([S:13](Cl)(=[O:15])=[O:14])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>[OH-].[Na+]>[C:7]1([S:13]([NH:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3])(=[O:15])=[O:14])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Komponenten

4

Edukt 2

HCID 5950L-AlanineHCID 7369Benzenesulfonyl chloride

Produkt 1

HCID 7114743(S)-2-(phenylsulfonamido)propanoic acidAusbeute 95 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 14798Sodium HydroxideLösungsmittel

Versuchsvorschrift

N-benzenesulfonylalanine was prepared by mixing equimolar quantities of alanine and benzenesulfonyl chloride at 60° C. in aqueous sodium hydroxide (200 mol%). A 95% yield was obtained. The method is set out in the previously mentioned book "Chemistry Of The Amino Acids".

Aufarbeitung

  1. customA 95% yield was obtained

Quellen und Nachweise

ORD-Eintrag
ord-426399edc266420e8327c4a0943796f2
Quelldatensatz
uspto-grants-1986_10
Patentnummer
US04618710

Notizen zur Reaktion

Wird geladen…