HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dimethyl Sulfoxide → HCID 14326857, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dimethyl Sulfoxide | HCID 679 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | Oxalyl chloride | HCID 65578 | — |
| Edukt | 1-(5-Isoquinolinesulfonyl)-3-hydroxy-5-methylpyrrolidine | HCID 21278320 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | HCID 14326857 | HCID 14326857 | — |
Reaktionsschritte
Then, in substantially the same manner as in Example 9, 2.34 g of the thus obtained 1-(5-isoquinolinesulfonyl)-3-hydroxy-5-methylpyrrolidine was reacted in dichloromethane with 1.08 g of oxalyl chloride, 0.67 g of dimethylsulfoxide and 0.60 g of triethylamine to obtain 1-(5-isoquinolinesulfonyl)-5-methyl-3-pyrrolidone.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04798897 |
| Quelldatensatz | uspto-grants-1989_01 |
| ORD ID | ord-b459180677ee4d34ba8d53b34902e5e5 |
| Quellennotiz | uspto-grants-1989_01 |