Methyl 2,4-dimethoxy-5-nitrobenzoate → Methyl 5-amino-2,4-dimethoxybenzoate

HRID 2293534Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2293534
[CH3:1][O:2][C:3]1[CH:12]=[C:11]([O:13][CH3:14])[C:10]([N+:15]([O-])=O)=[CH:9][C:4]=1[C:5]([O:7][CH3:8])=[O:6].[H][H]>O1CCCC1.[C].[Pd]>[NH2:15][C:10]1[C:11]([O:13][CH3:14])=[CH:12][C:3]([O:2][CH3:1])=[C:4]([CH:9]=1)[C:5]([O:7][CH3:8])=[O:6]

Komponenten

5

Edukt 2

HCID 11622839Methyl 2,4-dimethoxy-5-nitrobenzoateHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 16638096Methyl 5-amino-2,4-dimethoxybenzoate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A 4.00 g portion of methyl 2,4-dimethoxy-5-nitrobenzoate was dissolved in 200 ml of tetrahydrofuran, and 0.40 g of 10% palladium-carbon was added, followed by stirring for 12 hours at room temperature under normal pressure in an atmosphere of hydrogen. After removing insoluble matter by filtration, the solvent was evaporated under a reduced pressure to give 3.6 g of methyl 5-amino-2,4-dimethoxybenzoate.

Aufarbeitung

  1. customAfter removing insoluble matter
  2. filtrationby filtration
  3. customthe solvent was evaporated under a reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-fdf582eeabdf4a26ba561139d65a47bb
Quelldatensatz
uspto-grants-1997_11
Patentnummer
US05686482

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