Ammonia → α-Phenyl-2-benzothiazolemethanamine

HRID 2295486Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2295486
Cl.[NH2:2][CH:3]([C:10]1[S:11][C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[N:14]=1)[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.N>C(Cl)Cl>[NH2:2][CH:3]([C:10]1[S:11][C:12]2[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=2[N:14]=1)[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Komponenten

4

Edukt 2

HCID 222AmmoniaHCID 23318519HCID 23318519, Verbindung

Produkt 1

HCID 13342005α-Phenyl-2-benzothiazolemethanamine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

The hydrochloride was dissolved with aqueous ammonia and methylene chloride, the aqueous layer was extracted with two portions of methylene chloride. The combined methylene chloride extracts were washed with brine, dried over Na2SO4, filtered and concentrated in vacuo. 13.1 g. of white solid of desired producted was obtained, mp. 68°-70° C.

Aufarbeitung

  1. extractionthe aqueous layer was extracted with two portions of methylene chloride
  2. washThe combined methylene chloride extracts were washed with brine
  3. dry with materialdried over Na2SO4
  4. filtrationfiltered
  5. concentrationconcentrated in vacuo
  6. customof white solid of desired producted was obtained

Quellen und Nachweise

ORD-Eintrag
ord-437c62e85e7d49d09e9685a0b2096388
Quelldatensatz
uspto-grants-1984_01
Patentnummer
US04425338

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