Triethylamine → 2-Ethyltricyclo[3.3.1.1~3,7~]decan-2-yl prop-2-enoate

HRID 2298738Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2298738
[CH2:1]([C:3]1([OH:13])[CH:10]2[CH2:11][CH:6]3[CH2:7][CH:8]([CH2:12][CH:4]1[CH2:5]3)[CH2:9]2)[CH3:2].C(N(CC)CC)C.[C:21](Cl)(=[O:24])[CH:22]=[CH2:23]>CC(CC(C)C)=O>[C:21]([O:13][C:3]1([CH2:1][CH3:2])[CH:4]2[CH2:12][CH:8]3[CH2:7][CH:6]([CH2:11][CH:10]1[CH2:9]3)[CH2:5]2)(=[O:24])[CH:22]=[CH2:23]

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 13140Acryloyl chlorideHCID 44019512-Ethyl-2-adamantanol

Produkt 1

HCID 221688802-Ethyltricyclo[3.3.1.1~3,7~]decan-2-yl prop-2-enoateAusbeute 80 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7909Methyl Isobutyl KetoneLösungsmittel

Reaktionsbedingungen

Temperatur
40 °C

Versuchsvorschrift

180 g of 2-Ethyl-2-adamantanol, 303 g of triethylamine and 500 g of methylisobutyl ketone were mixed by stirring at 40° C. While stirring, 136 g of acrylic acid chloride was added dropwise to the mixture. After completion of the dropwise addition, the mixture was stirred for three more hours. Then, extraction and distillation were conducted to obtain 2-ethyl-2-adamantyl acrylate at the yield of 80%.

Aufarbeitung

  1. stirringWhile stirring
  2. additionAfter completion of the dropwise addition
  3. stirringthe mixture was stirred for three more hours
  4. extractionThen, extraction and distillation

Quellen und Nachweise

ORD-Eintrag
ord-f978f646b1ed48bebdf242c9bf9a7a76
Quelldatensatz
uspto-grants-2002_12
Patentnummer
US06495307B2

Notizen zur Reaktion

Wird geladen…