Ammonia → Urea, N,N'-bis(phenylmethyl)-

HRID 2300036

Reaktionsgleichung

Reaktionsgleichung von HRID 2300036
[NH2:1][C:2]([NH2:4])=[O:3].[CH2:5](N)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.N>>[CH2:5]([NH:1][C:2]([NH:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:3])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Komponenten

4

Edukt 3

HCID 222AmmoniaHCID 1176UreaHCID 7504Benzylamine

Produkt 1

HCID 72889Urea, N,N'-bis(phenylmethyl)-Ausbeute 599,4 %

Versuchsvorschrift

Heated was a mixture of urea 5.84 g (9.72 mmol) and benzylamine 25.0 g (23.3 mmol, 2.4 equivalents) at 150° C.-155° C. for 5 hours attaching with an air cooler. During the heating, observed was the ammonia gas evolution from colorless liquid reaction mixture. By cooling, it turned solidified at around room temperature. Purified was the reaction product by recrystallization from ethanol-benzene (1:1 mixture) to give N,N′-dibenzylurea 14.0 g as white fine needles (59.9% yield).

Aufarbeitung

  1. temperatureHeated
  2. customfrom colorless liquid reaction mixture
  3. temperatureBy cooling
  4. customturned solidified at around room temperature
  5. customPurified
  6. customby recrystallization from ethanol-benzene (1:1 mixture)

Quellen und Nachweise

ORD-Eintrag
ord-2828b789b1a44f70be3e7ce81ebdc615
Quelldatensatz
uspto-grants-2002_12
Patentnummer
US06498164B1

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