Hydrochloric Acid → 3-(Diethylsulfamoyl)benzoic acid

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a solution of 3-(chlorosulfonyl)benzoic acid (1.02 g, 4.62 mmol) in CH2Cl2 (100 mL) at 0° C. was added diethylamine (2.4 mL, 23 mmol). The resulting mixture was stirred at 0° C. for 3 h then worked up by adding 2N aqueous HCl and extracting 3× with EtOAc. The combined organic was washed with brine then dried over MgSO4 and concentrated under reduced pressure. The residue was used without further purification.

Herkunft & Nachweise