Boron tribromide → HCID 18372862, Verbindung

HRID 2301354Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2301354
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]3[O:11][C:12]4[C:17]([C:18](=[O:21])[C:19]=3[OH:20])=[C:16]([O:22][CH3:23])[CH:15]=[CH:14][CH:13]=4)=[CH:9][C:4]=2[O:3]C1.B(Br)(Br)Br>>[OH:3][C:4]1[CH:9]=[C:8]([C:10]2[O:11][C:12]3[C:17]([C:18](=[O:21])[C:19]=2[OH:20])=[C:16]([O:22][CH3:23])[CH:15]=[CH:14][CH:13]=3)[CH:7]=[CH:6][C:5]=1[OH:1]

Komponenten

3

Edukt 2

HCID 25134Boron tribromideHCID 98397442-(Benzo[1,3]dioxol-5-yl)-3-hydroxy-5-methoxy-chromen-4-one

Produkt 1

HCID 18372862HCID 18372862, VerbindungAusbeute 40.315.552 %

Versuchsvorschrift

The reaction was conducted according to the same procedure as Example 57 except that 60 mg (190 pmol) of the compound obtained in Example 4 instead of the compound obtained in Example 12 and 1.5 molar equivalents of boron tribromide (BBr3) were used. Then the resulting product was separated by preparative TLC to give 23 mg of the title compound in a yield of 40%.

Aufarbeitung

  1. customThen the resulting product was separated by preparative TLC

Quellen und Nachweise

ORD-Eintrag
ord-5c2757a6cef243a382d8ab72d0febe8f
Quelldatensatz
uspto-grants-2002_12
Patentnummer
US06500846B1

Notizen zur Reaktion

Wird geladen…