DL-alanine → 2-Methylpropyl 2-aminopropanoate hydrochloride

HRID 23018

Reaktionsgleichung

Reaktionsgleichung von HRID 23018
[NH2:1][CH:2]([C:4]([OH:6])=[O:5])[CH3:3].S(Cl)([Cl:9])=O.[CH2:11](O)[CH:12]([CH3:14])[CH3:13]>>[ClH:9].[CH2:11]([O:5][C:4](=[O:6])[CH:2]([CH3:3])[NH2:1])[CH:12]([CH3:14])[CH3:13]

Komponenten

4

Edukt 3

HCID 602DL-alanineHCID 6560IsobutanolHCID 24386Thionyl Chloride

Produkt 1

HCID 862001092-Methylpropyl 2-aminopropanoate hydrochloride

Versuchsvorschrift

A mixture of 35.64 g (0.4 mol) of D,L-alanine (Aldrich), 44 mL (0.6 mol) of thionyl chloride (Aldrich) and 200 mL of iso-butanol was refluxed for 1.5 hours. The volatiles were removed at reduced pressure at 90° C. under reduced pressure to give the title compound as an oil, which was used without further purification.

Aufarbeitung

  1. temperaturewas refluxed for 1.5 hours
  2. customThe volatiles were removed at reduced pressure at 90° C. under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-4925e8544ee04f8dbe2b5bf9ea58b95b
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06849650B2

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