Thionyl Chloride → Quinoline-6-carbonyl chloride hydrochloride
Reaktionsgleichung
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([OH:13])=O)=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:16])=O>>[ClH:16].[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([Cl:16])=[O:13])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1Komponenten
3
Versuchsvorschrift
6-Quinolinecarboxylic acid was refluxed in thionyl chloride for 30 min. The excess thionyl chloride was then removed by rotary evaporation (90° C.) to provide 6-quinolinecarbonyl chloride hydrochloride.
Aufarbeitung
- customThe excess thionyl chloride was then removed by rotary evaporation (90° C.)
Quellen und Nachweise
- ORD-Eintrag
- ord-4ec76eb7ff014f93be1aece7c341a9fd
- Quelldatensatz
- uspto-grants-2002_08
- Patentnummer
- US06429207B1
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