HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethyl pyruvate → N-(3,4Difluorophenyl)alanine Ethyl Ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethyl pyruvate | HCID 12041 | — |
| Edukt | 3,4-Difluoroaniline | HCID 77469 | — |
| Produkt | N-(3,4Difluorophenyl)alanine Ethyl Ester | HCID 15434838 | — |
Reaktionsschritte
Following General Procedure AA above and using 3,4-difluoroaniline (Aldrich) and ethyl pyruvate (Aldrich), the title compound was prepared. The reaction was monitored by tlc on silica gel (Rf=0.4 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06849650B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-5aea20dd2678425ea297ac123bd82da1 |
| Quellennotiz | uspto-grants-2005_02 |