Benzylamine → 2-(Pyridin-4-yl)-4-benzylamino-5-methyl-thieno-[2,3-d]-pyrimidine
Reaktionsgleichung
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:10]1[C:11]2[C:24]([CH3:25])=[CH:23][S:22][C:12]=2[N:13]=[C:14]([C:16]2[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=2)[N:15]=1>>[N:19]1[CH:18]=[CH:17][C:16]([C:14]2[N:15]=[C:10]([NH:8][CH2:1][C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:11]3[C:24]([CH3:25])=[CH:23][S:22][C:12]=3[N:13]=2)=[CH:21][CH:20]=1Komponenten
3
Versuchsvorschrift
With the procedure of Example 1, the reaction of benzylamine with 4-chloro-2-(pyridin-4-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-4-yl)-4-benzylamino-5-methyl-thieno-[2,3-d]-pyrimidine.
Quellen und Nachweise
- ORD-Eintrag
- ord-74f1bab781ca44998c3d0da4afb5b544
- Quelldatensatz
- uspto-grants-2002_08