5-Bromoisoquinoline → 7-Bromoisoquinoline N-oxide hydrochloride

HRID 2304241Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2304241
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][N:8]=[CH:9]2)=[CH:4][CH:3]=1.BrC1C=CC=C2C=1C=CN=C2.[ClH:23].BrC1C=CC=C2C=1C=C[N+]([O-:35])=C2>>[ClH:23].[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][N+:8]([O-:35])=[CH:9]2)=[CH:4][CH:3]=1

Komponenten

4

Edukt 3

HCID 7364875-BromoisoquinolineHCID 122574417-Bromoisoquinoline2×HCID 226657075-bromoisoquinoline N-oxide hydrochloride

Produkt 1

HCID 226659267-Bromoisoquinoline N-oxide hydrochloride

Versuchsvorschrift

Compound 37a was prepared from 7-bromoisoquinoline (Tyson, F. L., J. Am. Chem. Soc. 61, 183 (1939), this procedure gave a mixture of 7-bromoisoquinoline and 5-bromoisoquinoline) using the procedure described for 1a. The title compound was contaminated with the 5-bromoisoquinoline N-oxide hydrochloride. M.p. 107.0-112.5° C.

Aufarbeitung

  1. custom61, 183 (1939), this procedure gave

Quellen und Nachweise

ORD-Eintrag
ord-9e375c71fe184e6e8c332d2aed41e69c
Quelldatensatz
uspto-grants-2002_08
Patentnummer
US06432955B1

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