HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isobutyl pyruvate → N-(2-methylquinolin-6-yl)alanine Iso-butyl Ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isobutyl pyruvate | HCID 83084 | — |
| Edukt | 2-Methylquinolin-6-amine | HCID 103148 | — |
| Produkt | N-(2-methylquinolin-6-yl)alanine Iso-butyl Ester | HCID 54119157 | — |
Reaktionsschritte
Following General Procedure AA above and using 6-amino-2-methylquinoline (Lancaster) and iso-butyl pyruvate (prepared by following General Procedure AO above), the title compound was prepared. The reaction was monitored by silica gel tlc (Rf=0.44 in 50% EtOAc/hexanes). Purification was by flash chromatography (silica gel using 50% EtOAc/hexanes as the eluant).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06849650B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-e4defc8176564c78905f4f164eeb6e1d |
| Quellennotiz | uspto-grants-2005_02 |