Tetrahydrofuran → HCID 11253685, Verbindung

Beteiligte Stoffe

Reaktionsschritte

A total of 15 mmole of acrylic chloride was added dropwise to a mixture containing 10 mmole of the above-prepared α,α-dimethyl-1-adamantanemethanol, 20 mmole of triethylamine, and 40 ml of tetrahydrofuran, over about 30 minutes. After the completion of addition, the resulting mixture was stirred at room temperature for 6 hours. Water was added to the reaction mixture, and the resulting mixture was concentrated, and the concentrate was subjected to column chromatography on a silica gel to yield the title compound in a yield of 76%.

Herkunft & Nachweise