HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Naphthaleneacetic Acid → N-[(1-naphthyl)acetyl]-L-alanine Iso-butyl Ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Naphthaleneacetic Acid | HCID 6862 | — |
| Edukt | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| Produkt | N-[(1-naphthyl)acetyl]-L-alanine Iso-butyl Ester | HCID 15481767 | — |
Reaktionsschritte
Following General Procedure BB and using 1-naphthylacetic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared as a solid having a melting point of 69°-73° C. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06849650B2 |
| Quelldatensatz | uspto-grants-2005_02 |
| ORD ID | ord-1fe96754c66a433d836a5929de7f6a46 |
| Quellennotiz | uspto-grants-2005_02 |