O-(Tetrahydropyran-2-yl)hydroxylamine → 5-{[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl(3-{[(tetrahydro-2H-pyran-2-yloxy)imino]methyl}benzyl)amino]carbonyl}-1,2,4-benzenetricarboxylic Acid
Reaktionsgleichung
[CH:1]([C:3]1[CH:4]=[C:5]([CH:35]=[CH:36][CH:37]=1)[CH2:6][N:7]([C@@H:25]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27][CH2:26]1)[C:8]([C:10]1[CH:15]=[C:14]([C:16]([OH:18])=[O:17])[C:13]([C:19]([OH:21])=[O:20])=[CH:12][C:11]=1[C:22]([OH:24])=[O:23])=[O:9])=O.[O:38]1[CH2:43][CH2:42][CH2:41][CH2:40][CH:39]1[O:44][NH2:45]>>[C@@H:25]1([N:7]([CH2:6][C:5]2[CH:35]=[CH:36][CH:37]=[C:3]([CH:1]=[N:45][O:44][CH:39]3[CH2:40][CH2:41][CH2:42][CH2:43][O:38]3)[CH:4]=2)[C:8]([C:10]2[CH:15]=[C:14]([C:16]([OH:18])=[O:17])[C:13]([C:19]([OH:21])=[O:20])=[CH:12][C:11]=2[C:22]([OH:24])=[O:23])=[O:9])[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27][CH2:26]1Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
The product from Example 76E and O-tetrahydro-2H-pyran-2-ylhydroxylamine were processed as described in Example 76F to provide the title compound.