(4-Nitrophenyl)acetic acid → 2-[(4Nitrophenyl)acetamido]butyric acid iso-butyl ester

HRID 23078

Reaktionsgleichung

Reaktionsgleichung von HRID 23078
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][C:11]([OH:13])=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].[NH2:14][CH:15]([CH2:23][CH3:24])[C:16]([O:18][CH2:19][CH:20]([CH3:22])[CH3:21])=[O:17]>>[CH2:19]([O:18][C:16](=[O:17])[CH:15]([NH:14][C:11](=[O:13])[CH2:10][C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=1)[CH2:23][CH3:24])[CH:20]([CH3:21])[CH3:22]

Komponenten

3

Edukt 2

HCID 4661(4-Nitrophenyl)acetic acidHCID 13743360Isobutyl 2-aminobutyrate

Produkt 1

HCID 537955052-[(4Nitrophenyl)acetamido]butyric acid iso-butyl ester

Versuchsvorschrift

Following General Procedure BI above and using 4-nitrophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Aufarbeitung

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

Quellen und Nachweise

ORD-Eintrag
ord-bc0b5b8ae5a74a449c064857efab9915
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06849650B2

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