1,1-Dimethoxyethyl(dimethyl)amine → HCID 12146677, Verbindung
Reaktionsgleichung
[F:1][C:2]([F:25])([F:24])[C:3]1[CH:4]=[C:5]([N:9]2[CH2:14][CH2:13][N:12]([C:15]3[N:20]=[CH:19][C:18]([C:21](=[S:23])[NH2:22])=[CH:17][CH:16]=3)[CH2:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1.CO[C:28](OC)([N:30]([CH3:32])[CH3:31])[CH3:29]>>[CH3:31][N:30]([CH3:32])[C:28](=[N:22][C:21]([C:18]1[CH:19]=[N:20][C:15]([N:12]2[CH2:11][CH2:10][N:9]([C:5]3[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:1])([F:24])[F:25])[CH:4]=3)[CH2:14][CH2:13]2)=[CH:16][CH:17]=1)=[S:23])[CH3:29]Komponenten
3
Versuchsvorschrift
A mixture of intermediate 4 (0.013 mol) and 1,1-dimethoxy-N,N-dimethyl-ethanamine (0.021 mol) was allowed to stand overnight and then used without further purification, yielding N-[1-(dimethylamino)ethylidene]-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-3-pyridinecarbothioamide (intermediate 5).
Aufarbeitung
- customused without further purification
Quellen und Nachweise
- ORD-Eintrag
- ord-1d3297f8cf5a4e3f838039c10d843f35