3-Fluorophenylacetic acid → 2-[(3-Fluorophenyl)acetamido]butyric acid isobutyl ester

HRID 23087

Reaktionsgleichung

Reaktionsgleichung von HRID 23087
[F:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([OH:11])=O)[CH:5]=[CH:6][CH:7]=1.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[CH:3]=1)[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

Komponenten

3

Edukt 2

HCID 676173-Fluorophenylacetic acidHCID 13743360Isobutyl 2-aminobutyrate

Produkt 1

HCID 540199252-[(3-Fluorophenyl)acetamido]butyric acid isobutyl ester

Versuchsvorschrift

Following General Procedure BI above and using 3-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Aufarbeitung

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

Quellen und Nachweise

ORD-Eintrag
ord-69547e11d41b457b912899e3d2e59fa1
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06849650B2

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