Sodium Carbonate → HCID 20187493, Verbindung

Reaktionsgleichung

C(=O)([O-])[O-].[Na+].[Na+].Br[CH:8]([CH3:21])[C:9]([C:11]1[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[C:13]([O:19][CH3:20])[CH:12]=1)=[O:10].[CH3:22][C:23]1[CH:35]=[CH:34][C:26]([CH2:27][CH:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)=[CH:25][CH:24]=1>C(O)C>[CH3:22][C:23]1[CH:24]=[CH:25][C:26]([CH2:27][CH:28]2[CH2:33][CH2:32][N:31]([CH:8]([CH3:21])[C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[C:13]([O:19][CH3:20])[CH:12]=3)=[O:10])[CH2:30][CH2:29]2)=[CH:34][CH:35]=1

Komponenten

Versuchsvorschrift

5.4 g (0.05 mol) of sodium carbonate are added to a mixture of 13.65 g (0.05 mol) of 2-bromo-3',4'-dimethoxypropiophenone and 9.46 g (0.05 mol) of 4-(4-methylbenzyl)-piperidine in 50 ml of ethanol and the mixture is heated under reflux for 3 hours. It is then evaporated to dryness and the residue is passed through a column of silica using acetone as the eluant. This gives an oil, which is used as such.