2-(4-Fluorophenyl)acetic acid → 2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl ester

HRID 23090

Reaktionsgleichung

Reaktionsgleichung von HRID 23090
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:5]1[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=1)[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

Komponenten

3

Edukt 2

HCID 98372-(4-Fluorophenyl)acetic acidHCID 13743360Isobutyl 2-aminobutyrate

Produkt 1

HCID 541443992-[(4-Fluorophenyl)acetamido]butyric acid isobutyl ester

Versuchsvorschrift

Following General Procedure BI above and using 4-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Aufarbeitung

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

Quellen und Nachweise

ORD-Eintrag
ord-e4eda1727765451a9999f41a777ddc6c
Quelldatensatz
uspto-grants-2005_02
Patentnummer
US06849650B2

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