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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 2309237Erstellt: 24. Oktober 2026

L-Tryptophan → 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoic acid

https://huagongshe.com/de/reaction/2309237

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktL-TryptophanHCID 6305—
Edukt4-Chlorobenzoyl chlorideHCID 8501—
Produkt2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoic acidHCID 278752679,2%

Reaktionsschritte

By using 10 g of L-tryptophane and 9 g of 4-chlorobenzoyl chloride, and a method similar to that described in reference example 6, recrystallized from methanol-water there was obtained 13.3 g of 2-(4-chlorobenzoylamino)-3-(indol-3-yl)propionic acid in the form of colorless needle-like crystals. Melting point: 100°-102° C. [α]D25 -49.3° (C=1, methanol)

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04694017
Quelldatensatzuspto-grants-1987_09
ORD IDord-6cb5cc7566c5475a81c2b4ea40e7bc08
Quellennotizuspto-grants-1987_09