Hydrochloric Acid → HCID 20184577, Verbindung

HRID 2309886Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2309886
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([S:12]([Cl:15])(=[O:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5](O)=O.[CH3:16][NH2:17].[NH2:18][C:19]1[C:24]([NH2:25])=[CH:23][N:22]=[CH:21][N:20]=1.Cl>>[ClH:15].[CH3:1][O:2][C:3]1[CH:11]=[C:10]([S:12]([NH:17][CH3:16])(=[O:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5]1[NH:25][C:24]2[C:19](=[N:20][CH:21]=[N:22][CH:23]=2)[N:18]=1

Komponenten

5

Edukt 4

HCID 313Hydrochloric Acid2×HCID 6329MethylamineHCID 837034,5-DiaminopyrimidineHCID 201845804-(Chlorosulfonyl)-2-methoxybenzoic acid

Produkt 1

HCID 20184577HCID 20184577, Verbindung

Versuchsvorschrift

Prepared analogously to Example 50 from 2-methoxy-4-chlorosulfonyl-benzoic acid, aqueous methylamine solution, and 4,5-diamino-pyrimidine. The crude free base was converted into the hydrochloride with 2N hydrochloride acid, and the hydrochloride was purified by boiling with methanol.

Aufarbeitung

  1. customthe hydrochloride was purified

Quellen und Nachweise

ORD-Eintrag
ord-7dccb0ae0f414ebabf152484547b1d01
Quelldatensatz
uspto-grants-1987_09
Patentnummer
US04696931

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