4-Hydroxybenzoic Acid → 4-(1-Methylheptyloxycarbonyl)phenol

Beteiligte Stoffe

Reaktionsschritte

27.6 g of p-hydroxybenzoic acid and 39.0 g of (R)-2-octanol were refluxed for 10 hours in 300 ml of benzene in the presence of 0.5 ml of conc. sulfuric acid. Then, the reaction solution was cooled to the room temperature, and then concentrated and purified by column chromatography, to obtain 21.5 g of p-hydroxybenzoic acid 1-methylheptyl ester. (yield: 43%)

Herkunft & Nachweise