Sodium Dithionite → 4-chloro-3-hydroxy-10H-phenothiazine

Beteiligte Stoffe

Reaktionsschritte

A solution of Na2S2O4 (70 g) in water (500 ml) was added to a solution of 4-chloro-3H-phenothiazin-3-one (50 g) in DMF (1200 ml). The reaction mixture was stirred at room temperature for 3 hours and then poured in 5 liters of water. The resulting precipitate was then filtered to give the 4-chloro-3-hydroxy-10H-phenothiazine (95 %). m.p.: 110° C.

Herkunft & Nachweise