1-Ethyl-2-pyrrolidineethanamine → Phthalimidine

HRID 231865

Reaktionsgleichung

Reaktionsgleichung von HRID 231865
C(C1C=CC2[NH:7][C:8](=O)[C:9]3[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=3[CH:11]([OH:12])C=2C=1)#N.NCCC1CCCN1CC>>[C:11]1(=[O:12])[C:10]2[C:9](=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:8][NH:7]1

Komponenten

3

Edukt 2

HCID 144473471-Ethyl-2-pyrrolidineethanamineHCID 145020572-cyano-11-hydroxy-5, 11-dihydro-6H-dibenz[b,e]azepin-6-one

Produkt 1

HCID 10199Phthalimidine

Versuchsvorschrift

The same procedures as in Example 29 were repeated except for using 5.01 g of 2-cyano-11-hydroxy-5, 11-dihydro-6H-dibenz[b,e]-azepin-6-one and 12.82 g of 2-(aminoethyl)-1-ethylpyrrolidine as the starting materials. Thus, 0.93 g of 3-(2-amino-5-cyanophenyl)-2-[1-ethylpyrrolidin-2-yl) methyl]isoindolin-1-one (Compound 35) was obtained.

Quellen und Nachweise

ORD-Eintrag
ord-89e8d704b8a8469ab67f250f7617884e
Quelldatensatz
uspto-grants-1989_07
Patentnummer
US04849441

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