Isopropanol → 5,6-difluoro-N-(4-(3-(2-(3-(4-methylpiperazin-1-yl)propylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-1H-benzo[d]imidazol-2-amine

Reaktionsgleichung

[CH3:36][N:37]1[CH2:38][CH2:39][N:40]([CH2:43][CH2:44][CH2:45][NH2:46])[CH2:41][CH2:42]1.[CH3:47][CH:48]([OH:49])[CH3:50].[Cl:51][CH2:52][Cl:53].[F:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([NH:9][c:10]3[cH:11][cH:12][c:13]([O:16][c:17]4[n:18][cH:19][cH:20][cH:21][c:22]4-[c:23]4[n:24][c:25]([S:29]([CH3:30])(=[O:31])=[O:32])[n:26][cH:27][cH:28]4)[cH:14][cH:15]3)[n:8]2)[cH:33][c:34]1[F:35]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([nH:6][c:7]([NH:9][c:10]3[cH:11][cH:12][c:13]([O:16][c:17]4[n:18][cH:19][cH:20][cH:21][c:22]4-[c:23]4[n:24][c:25]([NH:46][CH2:45][CH2:44][CH2:43][N:40]5[CH2:39][CH2:38][N:37]([CH3:36])[CH2:42][CH2:41]5)[n:26][cH:27][cH:28]4)[cH:14][cH:15]3)[n:8]2)[cH:33][c:34]1[F:35]