Tetrahydrofuran → 3-(2-Chloro-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-ylmethylene)azetidine-1-carboxylic acid tert-butyl ester
Reaktionsgleichung
[C:34]([CH3:35])([CH3:36])([CH3:37])[O:38][C:39](=[O:40])[N:41]1[CH2:42][C:43](=[O:45])[CH2:44]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:1][O:2][P:3](=[O:4])([O:5][CH3:6])[CH2:7][c:8]1[cH:9][c:10]2[n:11][c:12]([Cl:23])[n:13][c:14]([N:17]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)[c:15]2[s:16]1.[CH3:25][Si:26]([N-:27][Si:28]([CH3:29])([CH3:30])[CH3:31])([CH3:32])[CH3:33].[Li+:24]>>[CH:7]([c:8]1[cH:9][c:10]2[n:11][c:12]([Cl:23])[n:13][c:14]([N:17]3[CH2:18][CH2:19][O:20][CH2:21][CH2:22]3)[c:15]2[s:16]1)=[C:43]1[CH2:42][N:41]([C:39]([O:38][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:40])[CH2:44]1
