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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 232311Erstellt: 26. Oktober 2026

P-Cresol → N-[2-(4-Methylphenoxy)ethyl]acetamide

https://huagongshe.com/reaction/232311

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktP-CresolHCID 2879—
Edukt2-Methyl-2-oxazolineHCID 70713—
LösungsmittelDichloromethaneHCID 6344—
ProduktN-[2-(4-Methylphenoxy)ethyl]acetamideHCID 538338—

Reaktionsschritte

Combine 5.0 g (0.046 mol) 4-methylphenol and 3.9 g (0.46 mol) 2-methyl-2-oxazoline under a nitrogen atmosphere and heat to 175° C. for 18 hours. After this time, cool the reaction mixture and add 50 mL of methylene chloride. Wash the organics with 3×10 mL of 10% potassium hydroxide, dry over sodium sulfate and remove the solvents to obtain the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04851526
Quelldatensatzuspto-grants-1989_07
ORD IDord-7c51a4b7facc43c296c5d45e86fa81e8
Quellennotizuspto-grants-1989_07