HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
P-Cresol → N-[2-(4-Methylphenoxy)ethyl]acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | P-Cresol | HCID 2879 | — |
| Edukt | 2-Methyl-2-oxazoline | HCID 70713 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | N-[2-(4-Methylphenoxy)ethyl]acetamide | HCID 538338 | — |
Reaktionsschritte
Combine 5.0 g (0.046 mol) 4-methylphenol and 3.9 g (0.46 mol) 2-methyl-2-oxazoline under a nitrogen atmosphere and heat to 175° C. for 18 hours. After this time, cool the reaction mixture and add 50 mL of methylene chloride. Wash the organics with 3×10 mL of 10% potassium hydroxide, dry over sodium sulfate and remove the solvents to obtain the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04851526 |
| Quelldatensatz | uspto-grants-1989_07 |
| ORD ID | ord-7c51a4b7facc43c296c5d45e86fa81e8 |
| Quellennotiz | uspto-grants-1989_07 |