2-(2,4-Dichlorophenoxy)propanoyl chloride → HCID 18633419, Verbindung

HRID 232352

Reaktionsgleichung

Reaktionsgleichung von HRID 232352
[Cl:1][C:2]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:3]=1[O:4][CH:5]([CH3:9])[C:6](Cl)=[O:7].[NH2:15][CH2:16][C@H:17]1[O:21][C@@H:20]([N:22]2[CH:29]=[C:28]([CH2:30][CH3:31])[C:26](=[O:27])[NH:25][C:23]2=[O:24])[CH2:19][C@@H:18]1[O:32][CH2:33][CH3:34]>>[Cl:1][C:2]1[CH:13]=[C:12]([Cl:14])[CH:11]=[CH:10][C:3]=1[O:4][CH:5]([CH3:9])[C:6]([NH:15][CH2:16][C@H:17]1[O:21][C@@H:20]([N:22]2[CH:29]=[C:28]([CH2:30][CH3:31])[C:26](=[O:27])[NH:25][C:23]2=[O:24])[CH2:19][C@@H:18]1[O:32][CH2:33][CH3:34])=[O:7]

Komponenten

3

Edukt 2

HCID 143033802-(2,4-Dichlorophenoxy)propanoyl chlorideHCID 186334585'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine

Produkt 1

HCID 18633419HCID 18633419, Verbindung

Versuchsvorschrift

In an analogous manner, from 2(RS)-(2,4-dichlorophenoxy)propionyl chloride (prepared from the acid) and 5'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine, there was obtained 5'-[2(RS)-(2,4-dichlorophenoxy)propionamido]-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine of melting point 121°-124° C.

Quellen und Nachweise

ORD-Eintrag
ord-5115850a93e645e7930f3b47c7e7e64a
Quelldatensatz
uspto-grants-1989_07
Patentnummer
US04851519

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