O-methylhydroxylammonium chloride → 2-Bromophenylglyoxylic Acid Methyl Ester-O-methyloxime

Beteiligte Stoffe

Reaktionsschritte

5.2 g (62 mmol) of 0-methylhydroxylamine hydrochloride is added to a solution of 10 g (41 mmol) of methyl 2-bromophenylglyoxylate in 30 ml of methanol, and the mixture is refluxed for 2 hours. The mixture is evaporated down, and the residue is taken up in ethyl acetate and washed with water. After drying and evaporating down, there remains 6.9 g (62%) of compound E.

Herkunft & Nachweise