Trifluoroacetic acid → 6-chloro-4'-(3-chlorophenyl)-1'-[3-(1,1-dioxo-thiomorpholin-4-yl)-propyl]-2'-(5-fluoro-2-methylphenyl)-spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione
Reaktionsgleichung
[CH3:1][O:2][CH:3]([Si:4]([CH3:5])([CH3:6])[CH3:7])[CH3:8].[Cl:9][c:10]1[cH:11][cH:12][c:13]2[c:17]([cH:18]1)[NH:16][C:15](=[O:19])[C:14]21[CH:20]([c:37]2[c:38]([CH3:44])[cH:39][cH:40][c:41]([F:43])[cH:42]2)[N:21]([CH2:33][CH2:34][CH2:35][Cl:36])[C:22](=[O:32])[CH2:23][CH:24]1[c:25]1[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]1.[OH:53][C:54]([C:55]([F:56])([F:57])[F:58])=[O:59].[S:45]1(=[O:51])(=[O:52])[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]1>>[Cl:9][c:10]1[cH:11][cH:12][c:13]2[c:17]([cH:18]1)[NH:16][C:15](=[O:19])[C:14]21[CH:20]([c:37]2[c:38]([CH3:44])[cH:39][cH:40][c:41]([F:43])[cH:42]2)[N:21]([CH2:33][CH2:34][CH2:35][N:48]2[CH2:47][CH2:46][S:45](=[O:51])(=[O:52])[CH2:50][CH2:49]2)[C:22](=[O:32])[CH2:23][CH:24]1[c:25]1[cH:26][c:27]([Cl:31])[cH:28][cH:29][cH:30]1
