HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(Trifluoromethyl)phenylboronic acid → N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(Trifluoromethyl)phenylboronic acid | HCID 2734389 | — |
| Edukt | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| Produkt | N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole | HCID 22998451 | 75% |
Reaktionsschritte
N-{5-[4-(trifluoromethyl)phenyl]thiophene-2-sulfonyl}pyrrole was prepared in the same manner as described in Example 32C using 4-trifluoromethylbenzene boronic acid and N-(5-bromothiophene sulfonyl)pyrrole. Purification by column chromatography using 2% ethyl acetate/hexanes gave the pure sulfonamide as a white powder in 75% yield.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05594021 |
| Quelldatensatz | uspto-grants-1997_01 |
| ORD ID | ord-6cb364a7ec3c4242bd5301897aaa98dd |
| Quellennotiz | uspto-grants-1997_01 |