Dimethylformamide → 7-bromo-N-[4-[[N-methyl-N-(tetrahydropyran-4-yl)amino]methyl]phenyl]-1,1-dioxo-2,3-dihydro-1-benzothiepine-4-carboxamide
Reaktionsgleichung
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:17]1)[CH:7]=[C:8]([C:14](=[O:15])[OH:16])[CH2:9][CH2:10][S:11]2(=[O:12])=[O:13].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:27][N:28]([CH:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1)[CH2:35][c:36]1[cH:37][cH:38][c:39]([NH2:40])[cH:41][cH:42]1.[CH3:48][CH2:49][N:50]([CH2:51][CH3:52])[CH2:53][CH3:54].[O:22]=[CH:23][N:24]([CH3:25])[CH3:26].[S:18]([Cl:19])([Cl:20])=[O:21]>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:17]1)[CH:7]=[C:8]([C:14](=[O:16])[NH:40][c:39]1[cH:38][cH:37][c:36]([CH2:35][N:28]([CH3:27])[CH:29]3[CH2:30][CH2:31][O:32][CH2:33][CH2:34]3)[cH:42][cH:41]1)[CH2:9][CH2:10][S:11]2(=[O:12])=[O:13]
