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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 235222Erstellt: 25. Oktober 2026

16-Hydroxyhexadecanoic acid → 2-Dimethylaminopyridine

https://huagongshe.com/reaction/235222

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt16-Hydroxyhexadecanoic acidHCID 10466—
EduktDicyclohexylcarbodiimideHCID 10868—
EduktCID 11268547HCID 11268547—
LösungsmittelTetrahydrofuranHCID 8028—
Produkt2-DimethylaminopyridineHCID 21885—

Reaktionsschritte

Following a procedure similar to that described in Example 12, but using 365 mg of radicicol, 681 mg of 16-hydroxyhexadecanoic acid, 20 ml of dry tetrahydrofuran, 516 mg of dicyclohexylcarbodiimide and a catalytic amount of dimethylaminopyridine, 661 mg of the title compound were obtained as crystals melting at 85°-86° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05597846
Quelldatensatzuspto-grants-1997_01
ORD IDord-6cdffb01c49c461caf7871ae4b574e83
Quellennotizuspto-grants-1997_01