Epichlorohydrin → HCID 23113189, Verbindung

HRID 2355800Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2355800
[O:1]1[CH2:5][CH2:4][CH2:3]C1.[OH:6][CH2:7][C:8]12[CH2:17][CH:12]3[CH2:13][CH:14]([CH2:16][C:10]([CH2:18][OH:19])([CH2:11]3)[CH2:9]1)[CH2:15]2.[H-].[Na+].[CH2:22]([CH:24]1[O:26][CH2:25]1)Cl>C(Cl)(Cl)Cl>[CH2:22]([O:6][CH2:7][C:8]12[CH2:15][CH:14]3[CH2:13][CH:12]([CH2:11][C:10]([CH2:18][O:19][CH2:3][CH:4]4[O:1][CH2:5]4)([CH2:16]3)[CH2:9]1)[CH2:17]2)[CH:24]1[O:26][CH2:25]1

Komponenten

6

Edukt 4

HCID 7835EpichlorohydrinHCID 8028TetrahydrofuranHCID 24758Sodium hydrideHCID 7030111,3-Adamantanedimethanol

Produkt 1

HCID 23113189HCID 23113189, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

300 ml of dehydrated tetrahydrofuran containing 19.6 g (0.1 mol) of 1,3-bis(hydroxymethyl)adamantane and 5.3 g (0.22 mol) of sodium hydride was stirred in a nitrogen atmosphere at the reflux temperature for 2 hours. Thereto was dropwise added 20.4 g (0.22 mol) of epichlorohydrin, followed by stirring at the reflux temperature for 12 hours. To the reaction mixture was added 200 ml of chloroform, followed by washing with water. The chloroform layer was dried with magnesium sulfate. The dried chloroform layer was subjected to distillation under reduced pressure for solvent removal, whereby was obtained a white solid and oily matter.

Aufarbeitung

  1. washby washing with water
  2. dry with materialThe chloroform layer was dried with magnesium sulfate
  3. distillationThe dried chloroform layer was subjected to distillation under reduced pressure for solvent removal
  4. customwhereby was obtained a white solid and oily matter

Quellen und Nachweise

ORD-Eintrag
ord-5772540f082e4804b2a7718f9593e7bf
Quelldatensatz
uspto-grants-2010_07
Patentnummer
US07754903B2

Notizen zur Reaktion

Wird geladen…