HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 23564Erstellt: 23. Oktober 2026
Water → 4-tert-Butoxycarbonylamino-1-(5-aminocarbonyl-2-pyridyl)piperidine
https://huagongshe.com/de/reaction/23564
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Water | HCID 962 | — |
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 6-Chloronicotinamide | HCID 80456 | — |
| Produkt | 4-tert-Butoxycarbonylamino-1-(5-aminocarbonyl-2-pyridyl)piperidine | HCID 11484042 | — |
Reaktionsschritte
A mixture of 3 g (0.015 mol) of the product of preparation 1, 1.5 g (0.015 mol) of triethylamine and 2.34 g (0.015 mol) of 6-chloronicotinamide in 60 ml of dimethylformamide is heated at 80° C. for 18 hours. After cooling, water is added and the product is filtered off. 2.8 g of the title compound are thus obtained. m.p. 255° C. dec.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US06852736B2 |
|---|
| Quelldatensatz | uspto-grants-2005_02 |
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| ORD ID | ord-cea0b8f2a83640e79fadf2be389be974 |
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| Quellennotiz | uspto-grants-2005_02 |
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