HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → Gsk-269984A
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Ethyl 6-(5-chloro-2-((4-chloro-2-fluorobenzyl)oxy)benzyl)picolinate | HCID 59384237 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | Gsk-269984A | HCID 23696973 | — |
Reaktionsschritte
Ethyl 6-[(5-chloro-2-{[(4-chloro-2-fluorophenyl)methyl]oxy}phenyl)methyl]-2-pyridinecarboxylate (421.4 mg, 0.97 mmol) was suspended in ethanol (4 ml) and 2M sodium hydroxide (1 ml) and heated at 90° C. for 1.75 hours. Reaction complete after about 1 hour.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07759369B2 |
| Quelldatensatz | uspto-grants-2010_07 |
| ORD ID | ord-70537d48873e4cba901481c0d29c3061 |
| Quellennotiz | uspto-grants-2010_07 |