Methanol → Benzoic acid, 2,5-diiodo-, methyl ester
Reaktionsgleichung
[I:1][C:2]1[CH:10]=[CH:9][C:8]([I:11])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].O=S(Cl)Cl.[CH3:16]O>>[I:1][C:2]1[CH:10]=[CH:9][C:8]([I:11])=[CH:7][C:3]=1[C:4]([O:6][CH3:16])=[O:5]Komponenten
4
Versuchsvorschrift
To a solution of 2,5-diiodobenzoic acid (1.00 g, 2.67 mmol) in anhydrous MeOH (15 mL) cooled in an ice-bath, SOCl2 (0.50 mL, 6.85 mmol) was cautiously added (exothermal reaction). After the addition, the solution was heated at reflux overnight. It was then concentrated in vacuo to give methyl 2,5-diiodobenzoate (1.04 g).
Aufarbeitung
- custom(exothermal reaction)
- additionAfter the addition
- temperaturethe solution was heated
- temperatureat reflux overnight
- concentrationIt was then concentrated in vacuo
Quellen und Nachweise
- ORD-Eintrag
- ord-d6d995b67d9b4283a2a6c14e3fbb5a26
- Quelldatensatz
- uspto-grants-2010_07
- Patentnummer
- US07763608B2
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