Hydrochloric Acid → 2-(3-Methoxyphenyl)cyclopropane-1-carboxylic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Hydrochloric Acid	HCID 313	—
Edukt	Cyclopropanecarboxylic acid, 2-(3-methoxyphenyl)-, ethyl ester	HCID 19358490	—
Lösungsmittel	Ethanol	HCID 702	—
Lösungsmittel	Sodium Hydroxide	HCID 14798	—
Produkt	2-(3-Methoxyphenyl)cyclopropane-1-carboxylic acid	HCID 13972233	—

Reaktionsschritte

The crude 2-(3-methoxy-phenyl)-cyclopropanecarboxylic acid ethyl ester is dissolved in 30 ml EtOH and 15 ml 1N NaOH. After stirring over night, the reaction mixture is acidified with 1N HCl and extracted with diethyl ether. After removal of the solvent 7.1 g of the 2-(3-methoxy-phenyl)-cyclopropanecarboxylic acid is obtained. This 2-(3-methoxy-phenyl)-cyclopropanecarboxylic acid is used without further purification.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07763728B2
Quelldatensatz	uspto-grants-2010_07
ORD ID	ord-115159adedc34e79819ccca64391392a
Quellennotiz	uspto-grants-2010_07