Methyl Methanesulfonate → 3-Amino-2-methyl-5,6-bis(4-methylphenyl)-1,2,4-triazine mesylate

HRID 2361860Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2361860
[NH2:1][C:2]1[N:3]=[N:4][C:5]([C:15]2[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=2)=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([CH3:14])=[CH:10][CH:9]=2)[N:7]=1.[CH3:22][S:23]([O:26]C)(=[O:25])=[O:24]>CO>[S:23]([OH:26])(=[O:25])(=[O:24])[CH3:22].[NH2:1][C:2]1[N:3]([CH3:22])[NH:4][C:5]([C:15]2[CH:16]=[CH:17][C:18]([CH3:21])=[CH:19][CH:20]=2)=[C:6]([C:8]2[CH:9]=[CH:10][C:11]([CH3:14])=[CH:12][CH:13]=2)[N:7]=1

Komponenten

4

Edukt 2

HCID 4156Methyl MethanesulfonateHCID 581031023-Amino-5,6-bis(4-methylphenyl)-1,2,4-triazine

Produkt 1

HCID 866497323-Amino-2-methyl-5,6-bis(4-methylphenyl)-1,2,4-triazine mesylate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

A mixture of 3-amino-5,6-bis(4-methylphenyl)-1,2,4-triazine (500 mg), methyl methanesulphonate (0.5 cm3) and methanol (10 cm3) was stirred at 40° for 24 hours and then evaporated to dryness. The resulting yellow solid was recrystallised from acetone giving the title compound as pale yellow needles,

Aufarbeitung

  1. customevaporated to dryness
  2. customThe resulting yellow solid was recrystallised from acetone giving the title compound as pale yellow needles

Quellen und Nachweise

ORD-Eintrag
ord-74a29c942b2c4c80a58efd4e91438d1d
Quelldatensatz
uspto-grants-2014_04
Patentnummer
US08691818B2

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